Why “Eat Less, Move More” Fails to Work

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We’ve all heard the age-old advice: “Eat less, move more.” But why does this simple formula not yield the desired results for everyone? Losing weight is already challenging, and maintaining that weight loss is even harder. This article explores the reasons behind the inefficacy of the “eat less, move more” approach and provides alternative strategies for achieving long-term success.

Hormonal Changes and Dysregulation

When we gain weight, hormonal changes occur in our bodies, leading to an increase in hunger and a decrease in satiety. These changes sabotage our efforts to “eat less” and make weight loss even more difficult to sustain. Here are some specific changes that take place:

  • Increased ghrelin levels: Ghrelin is the hormone responsible for triggering hunger.
  • Decreased adiponectin production: Fat cells produce adiponectin, a hormone that regulates weight. Reduced levels of adiponectin disrupt the body’s weight regulation pathways.
  • Leptin resistance: Leptin is the hormone that signals fullness. When we develop leptin resistance, we experience decreased fullness and altered signaling in weight regulation pathways.
  • Decreased GLP-1 hormone production: The small intestine produces GLP-1 hormone, which affects weight regulation, satiety, and insulin function.
  • Insulin resistance: Insulin resistance increases the risk of type 2 diabetes, excess visceral fat, fatty liver deposition, metabolic syndrome, and inflammation.
  • Inflammation: Weight gain leads to an increase in inflammation, which worsens insulin resistance and contributes to heightened blood clotting due to an inflammatory state.

Factors Exacerbating Hormonal Changes

Several factors exacerbate the hormonal changes that occur with weight gain. These factors include:

  • Lack of sleep: Inadequate sleep disrupts hormonal balance and contributes to weight gain.
  • Disruption of circadian rhythms: Our internal body clocks play a vital role in regulating metabolism and appetite. Disrupting these rhythms can impact weight management.
  • Emotional stress: Emotional stress triggers the release of cortisol, a stress hormone that can lead to weight gain.
  • Excessive exercise: While exercise is essential for maintaining a healthy weight, too much physical stress can actually hinder weight loss efforts.
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Strategies to Combat Weight Regain

With all these factors working against us, how can we fight back and maintain our weight loss in the long run? Here are nine strategies to consider:

  1. Understand the importance of reducing visceral fat: Visceral fat, located deep within the abdomen, poses a significant health risk. Reducing visceral fat improves metabolic health and lowers the risk of conditions like diabetes, hypertension, high cholesterol, fatty liver disease, and heart disease. Even a small decrease in weight can lead to significant health improvements.
  2. Take it slow: Sustainable changes happen gradually. Avoid extreme diet changes and focus on creating lasting habits.
  3. Build muscle: Strength training, such as lifting weights, helps build muscle, which boosts metabolism and aids in weight maintenance.
  4. Prioritize sleep: Aim for 7-8 hours of quality sleep each night to support healthy hormone regulation.
  5. Eat real foods: Incorporate more plants, lean animal proteins, and fiber-rich foods into your diet. These choices improve gut health and reduce dysbiosis (an imbalance in gut bacteria).
  6. Minimize ultra-processed foods: Stay away from cookies, chips, and candy. These foods lack dietary fiber, often contain excessive added sugars, unhealthy fats, and high sodium levels.
  7. Indulge occasionally: You don’t have to give up everything. Allow yourself some indulgence from time to time.
  8. Say no to sugary drinks: Minimize your consumption of soda, lemonade, juices, and sugary coffees. These drinks add empty calories and contribute to weight gain.
  9. Reduce stress: Stress not only affects hormones and inflammation but also influences our coping mechanisms. Find healthy ways to manage stress, rather than turning to comfort foods.
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For some individuals, anti-obesity medications can make a difference in fighting weight regain and overcoming the effects of metabolic adaptation. Just like treating chronic diseases, a long-term strategy that combines lifestyle changes and possibly medication can bring success.

In conclusion, achieving and maintaining weight loss is a complex process that requires a holistic approach. By understanding the hormonal changes that occur with weight gain and implementing these practical strategies, you can increase your chances of long-term success. Remember, it’s not just about eating less and moving more; it’s about making sustainable lifestyle changes that support your overall health and well-being.


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In Health,
Richa Mittal MD

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